Clinical Professor
Medical Director, Adult Metabolic Diseases Clinic
University of British Columbia, 1991, MD
University of British Columbia, 1996, Internal Medicine Residency
University of British Columbia, 1997, Endocrinology Fellowship
University of British Columbia, 1998, Metabolic Disease Fellowship
Clinical Interests
Research Interests

See Dr. Sirrs publications here

1: Laule C, Vavasour IM, Shahinfard E, Mädler B, Zhang J, Li DKB, MacKay AL, Sirrs SM. Hematopoietic Stem Cell Transplantation in Late-Onset Krabbe Disease: No Evidence of Worsening Demyelination and Axonal Loss 4 Years Post-allograft. J Neuroimaging. 2018 Feb 26.

2: Arends M, Biegstraaten M, Wanner C, Sirrs S, Mehta A, Elliott PM, Oder D, Watkinson OT, Bichet DG, Khan A, Iwanochko M, Vaz FM, van Kuilenburg ABP, West ML, Hughes DA, Hollak CEM. Agalsidase alfa versus agalsidase beta for the treatment of Fabry disease: an international cohort study. J Med Genet. 2018 Feb 7. pii: jmedgenet-2017-104863.

3: Sirrs S, Hannah-Shmouni F, Nantel S, Neuberger J, Yoshida EM. Transplantation  as disease modifying therapy in adults with inherited metabolic disorders. J Inherit Metab Dis. 2018 Feb 1.

4: Huang J, Khan A, Au BC, Barber DL, López-Vásquez L, Prokopishyn NL, Boutin M, Rothe M, Rip JW, Abaoui M, Nagree MS, Dworski S, Schambach A, Keating A, West ML, Klassen J, Turner PV, Sirrs S, Rupar CA, Auray-Blais C, Foley R, Medin JA. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017 May 12;5:241-258.

5: Wong EM, Lehman A, Acott P, Gillis J, Metzger DL, Sirrs S. Hypogonadotropic Hypogonadism in Males with Glycogen Storage Disease Type 1. JIMD Rep. 2017;36:79-84.

6: Randhawa N, Wilson L, Mann S, Sirrs S, Benavente O. Clinical Reasoning: A complicated case of MELAS. Neurology. 2016 Oct 18;87(16):e189-e195.

Gordon and Leslie Diamond Centre
Adult Metabolic Diseases Clinic
2775 Laurel St., Level 4
Vancouver, BC V5Z 1M9
phone: 6048755965
fax: 6048755967